Noopept Quick Summary
Also Known As:
Noopept (n-phenylacetyl-l-prolylglycine ethyl ester) (or GVS-111) is a synthetic noootropic substance derived from the infamous racetam family, which is known for providing an extra boost to cognitive abilities, memory, mood, and so much more! (It’s also one of the more affordable options out there!)
What Is Noopept?
We all must have heard of Piracetam – the runner up of the racetam family discovered in the early 1960s by Corneliu Giurgea, a renowned psychologist and chemist of his time.
Even though Piracetam was initially used for memory-related issues such as Alzheimer’s and Dementia – Giurgea realized that this drug also had significant brain-boosting and neuroprotective properties.
He then coined the term ‘Nootropics’ for Piracetam – and this term is now generalized for all the Nootropics out there!
Noopept shares a lot of similarities in structure and behavior with its forefather ‘Piracetam’.
But think of it as Gen Z!
It’s faster, sharper, and more potent than its counterpart!
Its effects are enjoyed by users throughout the globe as it upgrades cognition and memory.
It also elevates the mood!
Noopept is said to be hundreds of times more potent (or even 1000x! more) than Piracetam!
Noopept Claims: Backing them up With Research & Studies!
When it comes to Noopept, examine what research has shown, including the remarkable protective mechanisms in vitro.
It not only protects our cells against oxidative stress and free radicals but also tends to help recover their original state!
It has also increased the survival rates of cells that are met by toxic environments in the body.
This mechanism makes way for elevated mood states.
After being dosed with Noopept, the rats showed improvement in memory despite those nasty memory-declining chemicals acting on them!
Another experiment based on a similar Alzheimer’s model was implemented – in this one, the rats were robbed of their olfactory bulb.
From Wikipedia: The olfactory bulb (Latin: bulbus olfactorius) is a neural structure of the vertebrate forebrain involved in olfaction, the sense of smell. It sends olfactory information to be further processed in the amygdala, the orbitofrontal cortex (OFC) and the hippocampus where it plays a role in emotion, memory and learning.
And Noopept came to the rescue once again!
The Hippocampal region of the brain is crucial – it shapes us into who we are and plays a great role in personal behavior and development.
It showed an increase in the Brain-Derived Nootrophic Factor (BDNF) and the Nerve Growth Factor (NGF).
Especially in the Hippocampal region.
Both of these factors aid in neuronal growth and development – you can think of it as your brain getting bigger! (Metaphorically, not literally LOL)
This explains how it significantly affects cognition.
How Does Noopept Work?
If you have surfed here at SuperMindHacker.com well enough, you will have come across ‘Acetylcholine’ numerous times.
Its the brain’s primary neurotransmitter – which means it gets things done!
A LOT of things!
Noopept boosts levels of Acetylcholine via various signaling pathways.
It can cross the blood-brain barrier which means it acts directly on the brain.
There are times when our brain suffers in oxygen-deprived states – such scenarios can threaten the well-being and health of our minds.
When low on oxygen, the brain is saturated with glutamate – which has toxic effects on the brain.
Noopept makes its way to prevent and protect our brains against this crisis by regulating Acetylcholine levels and keeping glutamate levels at bay!
The sensitivity of glutamate receptors is increased so that they can bind to them more effectively instead of accumulating in regions of the brain.
This way, glutamate is put to good use and also prevented from excessive breakdown.
For those wondering, glutamate has excitatory effects that contribute to alertness.
What Is The Proper Dosage Of Noopept?
You need to familiarize your body with Noopept since your body does not produce it on its own.
It is available in liquid, tablet, and powder forms – it is often ingested via the sublingual (under the tongue) route for faster absorption.
Start with as little as 5 mg three times a day and top up towards a dose of 10-35 mg per day – the upper limit being 40 mg per day.
There is no authentic research or report on the life-threatening or lethal effects of overdosing on Noopept – but it is banned in the UK and that alone is a trigger warning not to OD on this substance.
Follow Recommended Dosing Guidelines for Noopept!
Taking it above the recommended dosage may impair short-term memory loss like this Reddit thread discusses here.
It is best to pop up this pill early in the morning after breakfast – taking it in the evening might disrupt your sleep cycle.
Noopept has a short half-life which poses a few debates and controversies in its use as a nootropic. I’ve seen some articles and websites claiming that it has a 2-3 hour half-life but it’s more like 45 minutes to an hour from my experience.
Cycling this drug is recommended – take it for 1-3 months after which taking a break for 25-30 days may keep the tolerance at bay.
You don’t want to continuously take noopept (or any other nootropic substance for that matter) without taking a break from it every so often.
What Are The Benefits Of Noopept?
Ready for a noopept review of it’s benefits? Well, there are many benefits that come with taking it as a nootropic ingredient, some of which I will detail below.
Enhanced Memory & Cognition
Due to the release of NGF and Acetyl Choline, this nootropic remained a popular choice for students – until it got banned (more on this later).
Users also claim to have achieved a longer attention span!
It has a mild stimulatory effect (it is not a direct stimulant though) due to its association with glutamate.
Noopept has been shown to decrease anxiety and stress clinically.
Anti-oxidant & Anti-inflammatory
It has neuroprotective effects that can delay the aging process of our brains.
Are There Any Side Effects Of Noopept?
Noopept in general is a very friendly and safe nootropic supplement.
Mild gastrointestinal disturbances are common, and sometimes:
Other Common Noopept Side Effects:
While these side effects might be experienced by some users, nothing too serious has surfaced yet, and it’s so far been proven as pretty safe to take.
I Recommend Adding This…
If you are experiencing headaches, you should consider adding in some citicoline along with it. (Actually, I recommend you do this anyways!)
Recommendation: While you can add a generic citicoline supplement to your own custom stack (nothing wrong with that), something even better would be to use an enhanced designer version like Performance Lab’s “Mind”
The main ingredient in it is cognizen (the most potent citicoline brand), plus they combine these 2 other powerful ingredients.
It’s basically like citicoline on steroids, and would be a perfect addition to Noopept.
I must warn you though, they frequently run out of stock! (I’m serious), so just be ready to put in a backorder if that is the case.
But don’t worry, they usually seem to catch up to the demand pretty quick.
Visit their Official Website to see if it’s currently in stock.
Noopept Warnings / Drug Interactions
For safety purposes, Noopept should be avoided in pregnant and lactating females.
Children below 18 years of age, individuals with liver issues, and those with hypertension are advised to seek alternative nootropics.
As always, you should consult with your doctor before taking any new supplement or nootropic substances to be on the safe side.
Where Can I Buy Noopept? (Legit Source)
In Russia, it is sold as an over the counter drug and is readily available.
It is really hard (or impossible) to get your hands on Noopept in the UK – whereas in the USA it is considered as a non-drug substance, and can be sold as a supplement. However, a drug application and labeling procedure are deemed necessary for you to import Noopept.
When buying it, you need to be careful when choosing a source, as there have been cases of fake noopept supplements floating around (including on Amazon and eBay).
Where I Personally Buy Noopept:
That’s why I recommend you purchase noopept from this nootropics manufactuer here.
This is beacause they provide a real certificate of analysis (proving it’s the real deal), and has a ton of awesome reviews and feedback. It’s also my personal choice for buying noopept.
They sell authentic and safe Noopept so you can feel at ease. (Plus its actually super affordable!)
* Not only that, they sell all forms of it, including: Powder, Capsules, & Sublingual Solution
Stacking Noopept (Custom Nootropic Stack Ideas)
With Piracetam & Alpha GPC – For A Quick Memory Boost
So that you can replenish your choline stores and unlock the ultimate cognitive portal!
All of these synergize with one another to amp up the Choline levels.
With Alpha-GPC & Phenibut – For Anxiolytic Effects
With Aniracetam / Phenylpiracetam & Sulbutiamine – For Excellent Cognition
For you to sharpen your motor skills with a dose of positive vibes!
Sulbutiamine can alleviate fatigued states and relax the mind.
With Huperzine A – For Superior Learning Experiences
Via amped-up levels of Acetylcholine!
With Choline, Theanine & Caffeine – For Brain Fluidity
A kickass dose of alertness and clarity can be imparted by this stack
With Armodafinil/Modafinil & Vitamin B6 – For A Relaxed And Focused Mind
And a kick of mental alertness!
Some Nootropic Supplements That Contain Noopept!
So far, I have come across only three (worth mentioning) Nootropic supplements that contain it as one of the main ingredients.
One of them goes by the name of Lumultra.
I like how they have synergized Noopept with Alpha-GPC – which can significantly enhance Acetylcholine levels for boosted cognition and performance.
It is more of a proprietary blend since the exact quantities of Noopept and Alpha-GPC (along with a few other ingredients) is not mentioned.
If you don’t want the headache of piecing together your own Noopept stack, Lumultra would be a great choice to get started!
2) NITROvit (Even Better!)
A more competitive stack would be NITROvit by Project NooYou.
This blend contains 37.5 mg of Noopept (excellent quantity) combined with 450 mg of Alpha-GPC along with 150 mcg of Huperzine A.
As mentioned in our section above, this makes an excellent stack that can help you eliminate brain fog, enhance brain fluidity, and protect you from aging!
Project NooYou’s NITROvit is an awesome pre-formulated stack for beginners and advanced nootropics users alike.
3) Ultra Racetam
The third and final Nootropic stack is called Ultra Racetam.
It combines 4 racetams for a charged up and amplified cognitive experience!
It contains just the right amount of Piracetam, Oxiracetam, Aniracetam, and of course, Noopept.
All of which you can purchase separately at our trusted source here.
These 4 members from the racetam family are known to easily synergize with one another.
You should consider this stack for hectic exam months!
And of course, remember to cycle them since this is a super jampacked cognitive stack!
However… A Better Option…
That being said, for most people, this is too much to handle.
And since Noopept is mostly sold as an individual supplement, it is super easy to create your own customized stack which can cater to the different needs of any individual!
Exotic Racetam Bundle!
Luckily, you can re-create a similar bundle with this EXOTIC RACETAM BUNDLE
Add that, along with some Authentic Noopept and you’re good to go!
This way, you can decide for yourself (custom stacking), how much of each racetam to add in. Yes, it does take a bit more research on your part, but it makes more sense in the long run, especially when you’re ready to change things up.
It simply gives you more options.
Why Is Noopept Banned In Some Countries?
Despite being a relatively safe drug, Noopept remains banned in the UK since it showed some problems related to the heart in a few college students.
It may also lead to psychosis if not dosed properly.
Such problems usually arise when a drug is abused – which is why we always recommend to tailor your regimen sensibly by following dosage guidelines, and rotating off of noopept with a completely different stack at least every couple of months.
Why Is Noopept’s Short Half-Life A Problem?
This popular smart drug does cross the blood-brain barrier (which is great!).
However, it is said that the peak only truly lasts for around 5-6 minutes and disperses completely after an hour.
This is why its use is usually debated upon as a nootropic substance.
So it is best to stack Noopept accordingly.
Dosing it properly also alters its half-life to make it last longer – just remember that you have to build the dose over a period of time to allow your body to become sensitized.
Noopept – The Ultimate Nootropic: Final Thoughts
Noopept is undoubtedly taking the Nootropic industry by storm.
Its effects are still under constant research and will soon be seen in almost every other Nootropic stack thanks to its amazing benefits!
Not to forget, many people enjoy stacking it themselves rather than relying on pre-formulated stacks.
However, dosing it properly is what makes the difference, so if you don’t feel confident that you can figure it all out on your own, maybe a pre-formulated stack like the ones I listed above are a better option for you.
Either way, noopept is one heck of a nootropic, and I don’t see it going anywhere in the foreseeable future.